Ezeadichie, Obinna Stanley and Ikekpeazu, Ebele Joy and Katchy, Amechi Uchenna and Wariso, Mina and Ugwu, C. C. and Onwuka, Osah Marthins (2025) Development of a Predictive Model for Hepatitis B Virus (HBV) Status Using Gender and Serum Biomarkers. Journal of CLINAM, 8 (2). pp. 1511-1517. ISSN 2639-9431
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Abstract
Early screening for the Hepatitis B Virus (HBV) is crucial for effective management and treatment, especially in resource-limited areas like Enugu State, Nigeria. This study aims to develop and validate a predictive model for HBV status. By integrating several factors, this research seeks to improve diag nostic accuracy and contribute to more effective HBV management, particularly in resource-limited settings. The study is focused on the following gender and serum biomarkers: alpha glutathione S transferase (α-GST), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) among patients at Enugu State University Teaching Hospital. Binary logistic re gression was employed to analyze the predictive power of these variables. The results indicate that AST is a statistically significant predictor of HBV status. In contrast, gender, alpha GST, ALP, and ALT were not statistically significant predictors in the model.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | mrs chioma hannah |
| Date Deposited: | 23 Jun 2025 11:51 |
| Last Modified: | 23 Jun 2025 13:21 |
| URI: | http://eprints.gouni.edu.ng/id/eprint/4906 |
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