Ndefo, Chinedum Joseph and Joshua, Parker Elijah and Anorue, Chukwuemeka Eleazar (2023) Evaluation of Hormonal and Biochemical Risk Factors for Benign Prostatic Hyperplasia: A Possible Way for Management and Prevention of Benign Prostatic Hyperplasia. Journal of Medical & Surgical Urology, 12 (3). pp. 1-7.
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Abstract
Objective: To identify some risk factors that contributes to the development and severity of BPH among the elderly in Enugu state, Nigeria. Study design: One hundred men aged 53 years-85 years were used for the study; the study was divided into two groups consisting of 50 male patients diagnosed with BPH and 50 healthy subjects. Methods: Twenty millilitre of whole blood samples were collected from each patient and the following parameters were investigated; oestrogen, testosterone, lipid profile, PSA, PAP, TAP, electrolyte concentration and antioxidant biomarkers. Results: It was found that increase in PAP, TAP, total cholesterol, TAG, LDL, oestrogen, potassium and sodium and decrease in levels of catalase, GPx , selenium, HDL and testosterone are risk factors for the development and severity of BPH. Conclusions: In view of this, modifiable lifestyles can be adopted for the prevention, management and treatment of BPH.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Faculty of Natural and Applied Sciences |
| Depositing User: | Uchenna Eneogwe |
| Date Deposited: | 20 Jun 2025 09:36 |
| Last Modified: | 20 Jun 2025 09:36 |
| URI: | http://eprints.gouni.edu.ng/id/eprint/4878 |
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