Phytochemical Profiling and GC- MS Analysis of Lantana camara Leaf Extract

Orji, Ebele A. and Ejere, Vincent C. and Orji, Christian T. and Anorue, Chukwuemeka Eleazar and Ossai, Nelson I. and Ojua, Eugene O. and Nwani, Christopher D. and Eyo, Joseph E. (2024) Phytochemical Profiling and GC- MS Analysis of Lantana camara Leaf Extract. Tropical Journal of Natural Product Research, 8 (7). pp. 7920-7927. ISSN 2616-0692

[img] Text
Phytochemical Profiling and GC- MS Analysis of Lantana camara Leaf Extract.pdf
Download (525kB)

Abstract

Identification of the phytochemical composition of plants is vital in new drug discovery and lead compound development for the management of infectious and non-infectious diseases. Lantana camara is an important medicinal essential oil-producing plant used in folklore medicine for the treatment of several diseases. This study evaluated the phytochemical composition and profiled the biologically active principles present in L. camara leaf extracts collected from Orba, Enugu State of Nigeria. The profiling of L. camara leaves methanol and aqueous extracts was done using qualitative and quantitative phytochemical and GC-MS techniques. The phytochemical screening showed the presence of alkaloids, terpenoids, flavonoids and other phenolic compounds. There were no significant differences (p > 0.05) in the steroids, saponins, terpenoids, glycosides and phenolic contents of methanol and aqueous extracts. The phenolic content in methanol (1563.85±0.07 mg/100g) and aqueous (1425.23±0.36 mg/100g) were significantly higher than other phytochemicals tested in this study. There was significantly (p < 0.05) higher alkaloids (506.74±5.52 mg/100g), flavonoids (372.04±8.39 mg/100g) and tannins (1426.43±7.43 mg/100g) in the methanol compared with the aqueous extracts with 349.92±13.10 mg/100g, 231.99±6.16 mg/100g and 1351.62±20.6 mg/100g respectively. The GC-MS analysis showed the presence of 39 biologically important compounds which included bis(2-ethylhexyl) phthalate, 9,19-cyclolanostan-3-ol-11-one acetate, 4H-1-benzopyran-4-one-5- hydroxy-2-(4-hydroxyphenyl), n-hexadecanoic acid, (Z)-7-hexadecenal, phytol acetate, phytol, 3,7,11,15-tetramethyl-2-hexadecen-1-ol and bicyclo [4.4.0] dec-2-ene-4-ol 2-methyl-9-(prop-1- en-3-ol-2-yl). The phytochemical analysis and the GC-MS profiling of the extracts of L. camara showed the presence of biologically important phytochemicals which could be responsible for the ethnomedicinal effects of L. camara.

Item Type: Article
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User: Uchenna Eneogwe
Date Deposited: 18 Jun 2025 13:38
Last Modified: 18 Jun 2025 13:38
URI: http://eprints.gouni.edu.ng/id/eprint/4863

Actions (login required)

View Item View Item
GOUNI Repository is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.