Evaluation of Analgesic Potential of Shumanniophyton magnificum Extract on Albino Rats

Anosike, C. Joy and Amadi, Emenike B. and Parker, Elijah Joshua and Asomadu, Rita O. and Jachike, Aneke Rowland (2024) Evaluation of Analgesic Potential of Shumanniophyton magnificum Extract on Albino Rats. Nigerian Journal of Biochemistry and Molecular Biology, 39 (3). pp. 141-145. ISSN 2659-0042

Text ajol-file-journals_752_articles_287480_679512be2bbec.pdf Download (568kB)

Abstract

Shumaniophyton magnificum is usually used in African folk medication to treat various diseases, especially fever, malaria, and pain. Pain is a well-known indicator of illness, and the medications used to treat pain are called analgesics. The primary issue with these medications continues to be their side effects. Natural herbs are safer substitutes. This study explored the analgesic potentials of the methanol extract of S. magnificum leaf using three distinct in vivo analgesic models: the Acetic Acid-Induced Writhing, Hot Plate, and Tail Flick Response Assessments. When compared to aspirin-treated groups, the S. magnificum extract significantly (p< 0.05) increased the latency time to thermal pain in comparison to groups that received pentazocine treatment. When compared to groups treated with pentazocine, the extract significantly (p<0.05) increased the pain reaction time of treated mice to thermal stimuli in a dose-dependent manner. In summary, the study's outcomes supporting the traditional use of S. magnificum for pain relief came from the extract's demonstrated pain-relieving properties

Item Type:	Article
Subjects:	Q Science > QD Chemistry
Divisions:	Faculty of Natural and Applied Sciences
Depositing User:	Uchenna Eneogwe
Date Deposited:	03 Jun 2025 09:27
Last Modified:	03 Jun 2025 09:27
URI:	http://eprints.gouni.edu.ng/id/eprint/4736

Actions (login required)

View Item