Assessment of Left Ventricular function and Aortic blood flow in children with Tetralogy of Fallot (TOF) attending two health institutions in Enugu Metropolis

Chinawa, Josephat M. and Ossai, Edmund N. and Chinawa, Awoere T. and Onyia, Jude T. (2024) Assessment of Left Ventricular function and Aortic blood flow in children with Tetralogy of Fallot (TOF) attending two health institutions in Enugu Metropolis. Malawi Medical Journal, 36 (4). pp. 283-287.

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Abstract

Tetralogy of Fallot (TOF) is the commonest cyanotic heart disease and the third commonest congenital heart defect after bicuspid aortic valve and ventricular septal defect1,2. It accounted for about 10% of all congenital cardiac defects3. Tetralogy of Fallot results from an anterior-cephalad deviation of the conal septum-; a common embryological malformation seen in children with TOF1,2. This deviation results in mal-aligned large ventricular septal defect (VSD), aortic overriding which results from the tortuous and mal-aligned ventricular septal defect. There is also right ventricular outflow tract obstruction and right ventricular hypertrophy. Mortality in untreated children with TOF is very high by 5 years of age. Intra-cardiac repair in children with uncomplicated TOF result in good long-term survival with a very considerable quality of life4.

Item Type: Article
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: mrs chioma hannah
Date Deposited: 29 May 2025 08:42
Last Modified: 29 May 2025 08:42
URI: http://eprints.gouni.edu.ng/id/eprint/4675

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