Screening of Phytochemicals and Biological Potential of Aqueous, Methanol and Hexane Extracts of Cylicodiscus gabunensis Stem Bark

Ayuk, E.L. and NJOKUNWOGBU, A.N and ILO, S.U. and Engwa, G.A. and ONI, T.O. (2015) Screening of Phytochemicals and Biological Potential of Aqueous, Methanol and Hexane Extracts of Cylicodiscus gabunensis Stem Bark. American Journal of Biochemistry, 5 (2). pp. 30-34.

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Abstract

This paper covers the preliminary investigation of different phytochemicals and the anti-microbial analysis of Cylicodisusgabunesis stem bark extracts as well as the thin layer chromatography (TLC) analysis of the methanol and hexane extracts respectively. The phytochemical screening of the aqueous, methanol and hexane extracts of the plant above revealed the presence of alkaloids, flavonoids, glycosides, tannins, saponins, and steroids at varying amount depending on the intensity of the colors observed. Anthraquinones were absent inaqueous extract while alkaloids, glycosides, phlobatannins and reducing sugars were absent in hexane extract. However, all the above mentioned chemical compounds were present in methanol extract. The presence of these compounds suggests that this plant has medicinal value. The antimicrobial analysis was carried out using the three extracts above on two test organisms, Salmonella, typhi and Staphylococcus aureus using streptomycine as a reference standard drug. The results showed appreciable inhibition of these organisms compared to the reference. The (TLC) analysis indicated the presence of other complex compounds whose identities need to be established by spectroscopic and elemental analysis.

Item Type:	Article
Subjects:	L Education > L Education (General) Q Science > Q Science (General)
Divisions:	Faculty of Natural and Applied Sciences
Depositing User:	miss ifeoma agbo
Date Deposited:	24 Apr 2019 09:47
Last Modified:	24 Apr 2019 09:47
URI:	http://eprints.gouni.edu.ng/id/eprint/1209

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