Phytochemical screening and in-vitro antioxidant activity of leaf extract of Petrocarpus soyauxii "Ora" and Petrocarpus santalinoides "Uturukpa"

EZE, CHIDIMMA (2018) Phytochemical screening and in-vitro antioxidant activity of leaf extract of Petrocarpus soyauxii "Ora" and Petrocarpus santalinoides "Uturukpa". Other thesis, Godfrey Okoye University Ugwuomu-Nike, Enugu.

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Abstract

This study examines the phytochemical composition and in-vitro antioxidant activity of leaf extracts of Pterocarpus soyauxii (ora) and Pterocarpus stantalinoides (uturukpa). Phytochemical tests were first carried out using standard methods, to establish the presence or otherwise of some specific bioactive compounds, such as alkaloids, saponins, tannins, flavonoids, polyphenols, steroids, anthraquinone, reducing sugar and terpernoid, which are known to exert some pharmacological activities. The result of the phytochemicals indicates that the presence of tannins (0.238) was higher in P. soyauxii than in P. santalinoides which contained 0.0691 of tannins. Pterocarpus soyauxii contained alkaloids (24.298), saponins (6.988), phenols (0.422), steroids (0.0148), flavonols (46.8) and flavonoids (0.876), while P. santalinoids does not contain alkaloids, but contained 6.988 of saponins, 0.352 of phenols and 0.0133 of steroids. The presence of flavonoids (1.572) and flavonols (185.6) were also observed. Quantitative estimates of other phytochemicals showed that P. santalinoides contained significantly higher concentration of flavonoids, (1.572) and flavonols (185.6). as compared to P. soyauxii which contained (0.876) of flavonoids, and (46.8) of flavonols. The results of this study also showed that leaf extracts of P. soyauxii and P. santalinoides possessed reducing power ability, as well as the ability to scavenge hydrogen peroxide, which could otherwise result in oxidative stress conditions in vivo. Compounds  with  reducing  power ability indicate  that  they  are  electron  donors  and  can  reduce  the  oxidized  intermediates  of  lipid  peroxidation  processes,  so  that  they  can  act  as  primary  and  secondary antioxidants.

Item Type:	Thesis (Other)
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Natural and Applied Sciences
Depositing User:	miss Chidimma Sophia Eze
Date Deposited:	08 Oct 2018 13:01
Last Modified:	08 Oct 2018 13:01
URI:	http://eprints.gouni.edu.ng/id/eprint/844

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