ANTIMICROBIAL EFFICACY OF Dialium guineense (“ICHEKU”) AND Irvingia gabonensis(“UJIRI”) against Streptococcus mutans AND Candida albicans

Jonathan, chinemerem ANTIMICROBIAL EFFICACY OF Dialium guineense (“ICHEKU”) AND Irvingia gabonensis(“UJIRI”) against Streptococcus mutans AND Candida albicans. Antimicrobial efficacy of Dialium guineense and Irvingia gabonensis against Streptococcus mutans and Candida albicans. (Submitted)

	Text 2222.docx Download (26kB)
	Text 11111.docx Download (101kB)

Abstract

The antimicrobial activities of the aqueous, ethanol and methanol stem extracts of Dialium guineense and Irvingia gabonensis were evaluated against Candida albicans and Streptococcus mutans using the agar well diffusion technique. The results reveal that the crude aqueous, ethanol and methanol extracts possess antimicrobial activities on the tested organisms with the exception Dialium guineense which showed no zone of inhibition against Streptococcus mutans. The highest zone of inhibition was exerted by Irvingia gabonensis against C. albicans and was 24 mm. The minimum inhibitory concentration (MIC) was done by two methods; the broth dilution method and the microdilution method. The first method was between 128 256 mg/ml while the second method which tests for the sensitivity of organisms against very low concentration of extracts only caused an inhibition on C. albicans at 1000ug. Also, the minimum biocidal concentration (MBC) of the aqueous and ethanol extracts on majority of the organisms was above 256 mg/ml Meanwhile, only C. albicans showed MBC to the aqueous extract of Irvingia gabonensis at 120 mg/ml In addition, the phytochemical screening revealed the presence of flavonoids, alkaloids, tannin, saponins, and oxalates. The results of this work suggest further exploitation of the stem of D. guineense to possibly unveil its potential use for the treatment of diseases.

Item Type:	Article
Subjects:	Q Science > QR Microbiology > QR180 Immunology
Depositing User:	Master Chinemerem Jonathan
Date Deposited:	28 Sep 2018 11:56
Last Modified:	28 Sep 2018 11:56
URI:	http://eprints.gouni.edu.ng/id/eprint/546

Actions (login required)

View Item